Drug Interaction With Anti Diabetic Drugs - 772 Words

Faculty of pharmacy Pharmacology and toxicology department Clinical Pharmacology PO512 Assignment Drug interaction with Anti-diabetic drugs Amany Essma Ahmed 136097 Prof.Dr. Amany El-Brairy Assistants AL. Maha Shouman AL. Heba Hossam Introduction Diabetes is considered as insulin secretion deficiency that diagnosed easily by low blood glucose level (Wilson, 2001). There are very common signs and symptoms such as polyphagia, polyuria and polydipsia, thus major complications will be observed from gangrene, glaucoma, kidney failure, and nervous diseases to cardiovascular complications (Wilson, 2001). Classifications of anti-diabetic drugs A. Injected insulin According to Wilson (2001), it is a chemically synthetic injected†¦show more content†¦Drug interactions According to Inzucchi and McGuire (2008), 1. Insulin, alcohol, MAOI and salicylates: hypoglycemia 2. Dicumarol, chloramphenicol and MAOI: reduce hepatic metabolism of sulphonylurea 3. Sulfonamide, probencid and salicylates: reduce urinary excretion of sulphonylurea 2. Biguanides e.g. metformin Mechanism of action Anti-hyperglycemia will be achieved through many steps; decreasing glycogen breakdown, improving insulin sensitivity in the tissues and decreasing glucose synthesis by the liver and its absorption by the intestine (Inzucchi and McGuire, 2008). Uses Used mainly in controlling hyperglycemia, either alone or in combination with sulphonylurea. Also it has anti-hypertension effect (Inzucchia and McGuire, 2008). Adverse effects Cause lactic acidosis and many GIT problems such as anorexia, nausea and vomiting (Inzucchi and McGuire, 2008). Drug interactions As Inzucchi and McGuire (2008) said that, 1. Deficiency of vitamin B12 and folic acid when taken with it: decrease their absorption 2. Ibubrufen, propranolol, nifedipine and glyburide: hyperglycemia 3. Quinidine, cimetidine and trimethoprim: reduce metformin elimination and increase its serum concentration. 3. Alpha glucosidase inhibitors e.g. Miglitol Mechanism of action They inhibits alpha amylase enzyme that is responsible for carbohydrate digestion and so delay their absorption from the intestine in order to manage diabetes (Nathan, et. al., 2008). Uses Combine withShow MoreRelatedTypes And Types Of Type 2 Diabetes Mellitus1046 Words   |  5 Pagescomplications, the patients are prescribed with multiple treatment modalities such as oral hypoglycemic drugs and insulin sensitizers. The advancement in research has helped in identifying various gluco-regulatory receptors as well as novel class of drugs for these targets that are found to have effective control on diabetes as well as its complications [6]. The primary classes of anti-diabetic drugs include sulfonylureas, meglitinides, biguanides, thiazolidinediones, alpha-glucosidase inhibitors, amylinRead MoreThe New Class Of Anti Diabetic Drugs2008 Words   |  9 Pagesare the new class of anti-diabetic drugs that are the first to be able to manage glycaemia goals. Troglitazone was first approved for the market in 1997, but it was withdrawn from the market by 2000. After the withdrawal of troglitazone, rosiglitazone and pioglitazone were introduced in 1999 as potentially safer alter natives. However, currently rosiglitazone is under black box warning for increased risk of cardiovascular disease and pioglitazone is in a nutshell as the drug required more investigationRead MoreDiabetes Mellitus : A Group Of Metabolic Diseases Characterized By Hyperglycemia Resulting From Defects1463 Words   |  6 Pages(R/N) Drug Class Antidiabetic agent Pharmacokinetics Well absorbed from subcutaneous administration and metabolized by liver spleen, kidney and liver. Indications Diabetes mellitus Mechanism of Actions Binds to the receptors located on the target cells triggers changes in cellular activity Increase the glucose uptake by cell membrane of the skeletal muscle cells and fat cells, increased protein synthesis Side Effects Hypoglycemia, allergic reactions Significant Interactions Drug-Drug: betaRead MoreEfficacy Of Lisinopril1126 Words   |  5 PagestheIR quality of life have been improving in the past 100 due to changes in medicine and in public health (Mattes et al., 2013). Patients are placed on multiple medications at the same time and it important to understand their safety, efficacy, drug interaction, and toxicity (Mattes et al., 2013). As Mr. Cynthia Nurse practitioner, my job is to understand what affect her prescribing medication is having on her body. I have place Mrs. Cynthia on Lisinopril for her hypertension and metformin for her typeRead MoreComplications and Prevalence of Diabetes1391 Words   |  6 Pageseither due to insufficient insulin production or to the inability of cells to respond to insulin. Diabetes can cause a lot of long-term complications that affect different parts of the body. It can cause eye complications such as glaucoma, cataracts, diabetic retinopathy, and blindness. Foot complications that can lead to amputation can also result from uncontrolled diabetes. Skin infections and disorders are more common to people with diabetes. It also causes heart problems, ischemia, stroke, kidneyRead MorePharmacokinetic and Pharmacodynamic Interaction of aqueous extract of Cassia auriculata L. leaves and Metformin in rats.1533 Words   |  7 Pages1. Introduction Cassia auriculata L. (CA) is profoundly used as a tonic, astringent, anti-diabetic, conjunctivitis and opthalmia in Ayurvedic medicine (Subhadradevi et al., 2011). It is one of the principle constituent of Avaarai panchaga chooranam; an Indian herbal formulation used in the treatment of diabetes to control the blood sugar level (Berman et al., 2001). Cassia species, are rich sources of polyphenols, anthraquinone derviatives, flavanoids, polysaccrides, saponins, tannins and steroidsRead MoreMechanistic Analysis Of Biguanide Induced Inhibition Of Oxidative Phosphorylation1460 Words   |  6 Pagescompounds into the mitochondria varies on hydrophobicity, in general anti-diabetic biguanides can passively diffuse while anti-malarial compounds cannot. These findings are a next step in trying to understand the biochemical interactions this family of compounds has within mitochondria. DISCUSSION Our findings demonstrate that all five biguanide compounds tested inhibited oxidative phosphorylation (OP) through an interaction with complex I in the electron transport chain (ETC). Through ElectronRead MoreFormulation Manufacturing Issues of Levadopa/ Carbidopa Combinations1543 Words   |  6 PagesFormulation Manufacturing Issues Levodopa/Carbidopa (Sinemet ®) – Synthetic Drug The most effective drug used in the treatment of Parkinson’s disease is levodopa. When Levodopa is consumed on its own, it evidentially causes nausea and vomiting. Due to this factor a combination therapy with the drug carbidopa is essential in the treatment of Parkinson’s disease to avoid side effect. The most popular carbidopa/levodopa pharmaceutical formulation is called Sinemet ®. Carbidopa/levodopa can be foundRead MoreThe Herbal And Dietary Supplement Market1501 Words   |  7 Pagesimportance of food in treatment and prevention of diseases since regular consumption of synthetic drugs sometimes cause organ failure and so many other effects. Again, consumers have the belief that food like substances are either harmless or less toxic as compared to conventional drugs, furthermore nutraceuticals are cheaper and are safe with regards to avoiding the side effects associated with drugs (Tapans et al., 2008). CLASSIFICATION Nutraceuticals can be isolated nutrients herbal products, dietaryRead MoreDiabetic Case Study877 Words   |  4 PagesThe American Association of Clinical Endocrinologist (AACE) treatment goals are individualized and aimed at lowering A1C and prevention of hypoglycemia along with decreased comorbidities associated with diabetes. Diabetics who are at an increased risk for hypoglycemia include: a diagnosis of greater than 15 years, advanced macrovascular disease, hypoglycemia unawareness, limited life expectancy and severe comorbidities (Garber, Blonde, Bush, Einhorn, Garber,et al., 2017). In addition Fowler (2010)

John Jacob Astor - Biography of Richest American

John Jacob Astor was the wealthiest man in America in the early 19th century, and when he died in 1848 his fortune was estimated to be at least $20 million, an astounding sum for the time. Astor had arrived in America as a poor German immigrant, and his determination and business sense led him to eventually create a monopoly in the fur trade. He diversified into real estate in New York City, and his fortune increased as the city grew. Early Life John Jacob Astor was born on July 17, 1763 in the village of Waldorf, in Germany. His father was a butcher, and as a boy John Jacob would accompany him to jobs butchering cattle. While a teenager, Astor earned enough money at various jobs in Germany to enable him to relocate to London, where an older brother was living. He spent three years in England, learning the language and picking up any information he could about his ultimate destination, the North American colonies which were rebelling against Britain. In 1783, after the Treaty of Paris formally ended the Revolutionary War, Astor decided to sail to the young nation of the United States. Astor left England in November 1783, having bought musical instruments, seven flutes, which he intended to sell in America. His ship reached the mouth of the Chesapeake Bay in January 1784, but the ship became stuck in ice and it would be two months before it was safe for the passengers to land. Chance Encounter Led to Learning About the Fur Trade While languishing aboard ship, Astor met a fellow passenger who had traded for furs with the Indians in North America. Legend has it that Astor quizzed the man extensively on the details of fur trading, and by the time he set foot on American soil Astor had resolved to enter the fur business. John Jacob Astor eventually reached New York City, where another brother was living, in March 1784. By some accounts, he did enter the fur trade almost immediately and soon returned to London to sell a shipment of furs. By 1786 Astor had opened a small shop on Water Street in lower Manhattan, and throughout the 1790s he kept expanding his fur business. He was soon exporting furs to London and to China, which was emerging as a huge market for the pelts of American beavers. By 1800 it was estimated that Astor had amassed nearly a quarter of a million dollars, a considerable fortune for the time. Astors Business Continued to Grow After the Lewis and Clark Expedition returned from the Northwest in 1806 Astor realized he could expand into the vast territories of the Louisiana Purchase. And, it should be noted, the official reason for Lewis and Clarks voyage was to help the American fur trade expand. In 1808 Astor combined a number of his business interests into the American Fur Company. Astors company, with trading posts throughout the Midwest and Northwest, would monopolize the fur business for decades, at a time when beaver hats were considered the height of fashion in America and Europe. In 1811 Astor financed an expedition to the coast of Oregon, where his employees founded Fort Astoria, an outpost at the mouth of the Columbia River. It was the first permanent American settlement on the Pacific Coast, but it was destined to fail due to various hardships and the War of 1812. Fort Astoria eventually passed into British hands. While the war doomed Fort Astoria, Astor made money in the final year of the war by helping the United States government finance its operations. Later critics, including the legendary editor Horace Greeley, accused him of having profiteered in war bonds. Astor Accumulated Vast Real Estate Holdings In the first decade of the 19th century Astor had realized that New York City would continue to grow, and he began buying up real estate in Manhattan. He amassed vast property holdings in New York and the surrounding area. Astor would eventually be called the citys landlord. Having grown tired of the fur trade, and realizing it was too vulnerable to changes in fashion, Astor sold all his interests in the fur business in June 1834. He then concentrated on real estate, while also dabbling in philanthropy. Legacy of John Jacob Astor John Jacob Astor died, at the age of 84, in his house in New York City on March 29, 1848. He was by far the richest man in America. It was estimated that Astor had a fortune of at least $20 million, and he is generally considered the first American multimillionaire. Most of his fortune was left to his son William Backhouse Astor, who continued to administer the family business and philanthropic endeavors. John Jacob Astors will also included a bequest for a public library. The Astor Library was for many years an institution in New York City, and its collection became the foundation for the New York Public Library. A number of American towns were named for John Jacob Astor, including Astoria, Oregon, the site of Fort Astoria. New Yorkers know the Astor Place subway stop in lower Manhattan, and there is a neighborhood in the borough of Queens called Astoria. Perhaps the most famous instance of the Astor name is the Waldorf-Astoria Hotel. John Jacob Astors grandsons, who were feuding in the 1890s, opened two lavish hotels in New York City, the Astoria, named for the family, and the Waldorf, named for John Jacob Astors native village in Germany. The hotels, which were located at the present site of the Empire State Building, were later combined into the Waldorf-Astoria. The name lives on with the current Waldorf-Astoria on Park Avenue in New York City. Gratitude is expressed to the New York Public Library Digital Collections for the illustration of John Jacob Astor.

Hiv, Or Human Immunodeficiency Virus - 1432 Words

Currently, 1.2 million people in the United States have been diagnosed with HIV, or human immunodeficiency virus, with the number of new HIV diagnoses declining by 19% from 2005 to 2014 (aids.gov). This decrease in diagnoses is due to the new medical advancements and scientific findings, specifically the discovery of nonprogessers, broadly neutralizing antibodies (bNAbs), and how these bNAbs can offer a new insight on HIV treatment and prevention. The HIV infection and disease progression varies from person to person. It can be divided into three main categories based on how fast the disease progresses into full-blown AIDS as well as each individual’s lab results. The top and most severe tier of HIV is rapid progression of HIV. With rapid progression, AIDS developed within three years of the diagnosis. The next tier is intermediate progression. For individuals within this tier, the time it takes for HIV to progress to AIDS varies between three and ten years after the HIV virus was found to be detectable within their blood. The last tier is composed of long-term non-progressors, or LTNPs (Kumar). Despite having been diagnosed with HIV, those that fall within the LTNP category do not show symptoms. They make up only about one to five percent of the total HIV population. To be considered a long term non progressor, one must remain symptom free, maintain a low viral load without antiretroviral treatment and have a CD4+ T cell count above 500/mm3 for more than seven yearsShow MoreRelatedHuman Immunodeficiency Virus ( Hiv )1359 Words   |  6 PagesThis paper explores the human immunodeficiency virus (HIV) as well as the simian immunodeficiency virus (SIV). The virus has infected two million adults and children by the year 2005 already. The virus continues to race around the world, and new HIV infections are at 50,000 per year (Martine Peeters, Matthieu Jung, Ahidjo Ayouba) (2013). The final outcome of the HIV infection is Acquired Immune Deficiency Syndro me (AIDS). There are many treatments that have developed to help the large numberRead MoreHiv And Human Immunodeficiency Virus Essay1208 Words   |  5 PagesHIV has been a pandemic that has affected the world relentlessly for many years in a never-ending circle. HIV, or Human Immunodeficiency Virus, is the virus that is spread through certain bodily fluids and can lead to AIDS (Acquired Immunodeficiency Syndrome). HIV attacks the immune system by destroying CD4+ T cells, which leaves the person infected with HIV vulnerable to other infections, diseases, and other complications.1 Once this virus is acquired, the human can never fully rid itself of thisRead MoreHuman Immunodeficiency Virus ( Hiv )884 Words   |  4 Pages(2010), Human Immunodeficiency Virus (HIV) is a virus that affects the human immune system, leading to a chronic, progressive sickness that leaves people susceptible to opportunistic infections. When the body no longer can fight or resist infections, the condition is at this point referred to as AIDS, which means Acquired Immunodeficiency Syndrome. Averagely, it has been found to take more than ten years to develop from initial infection of HIV to AIDS. Though simple in description, HIV and AIDSRead MoreThe Human Immunodeficiency Virus ( Hiv )862 Words   |  4 Pagesshown that the Human Immunodeficiency Virus (HIV) is the cause of AIDS. More than 33.4 million people worldwide are infected with the HIV virus today. HIV stands for Human Immunodeficiency virus. HIV is a virus similar to that of the flu or common cold. The differentiating factor is that with the flu and cold, your body will eventually clear the virus out of your system, but with the HIV virus, the immune system cannot clear it. Getting HIV means you have it for life. The virus immediately beginsRead MoreThe Human Immunodeficiency Virus ( Hiv )948 Words   |  4 PagesThe Uses of Blood by the HIV Virus Blood-borne diseases have contributed greatly to poor health outcomes among individuals and communities. Though blood fulfills various functions to ensure our survival, it can also act as the mechanism through which we become diseased. Understanding the characteristics of such infectious diseases is essential to preventing further cases. In this paper I will discuss how the human immunodeficiency virus (HIV) uses blood to cause illness within the infected individualRead MoreHuman Immunodeficiency Virus ( Hiv )1261 Words   |  6 PagesHuman Immunodeficiency Virus Human immunodeficiency virus (HIV) has become more commonly seen in the world. It is important to show compassion rather than judging that patient based on a virus. The hygienist plays an important role in making the patient feel comfortable and in a judgment free environment. The patient should not feel as if the disease or virus defines the overall character of the patient. Standards precautions are still the same when treating all patients with or without a compromisingRead MoreHiv And Human Immunodeficiency Virus1205 Words   |  5 PagesWhat is HIV? HIV is a fatal disease which stands for â€Å"Human Immunodeficiency Virus† it is a failure to the immune system to protect the body from any infections. This virus causes a condition called acquired immunodeficiency syndrome. When HIV is left untreated it leads to another disease called â€Å"AIDS†. It can occur in any age, race, sex or sexual orientation. The highest risk of contracting HIV is having unprotected sex and sharing needles with others. Another factor are people that have STI’s andRead MoreThe Human Immunodeficiency Virus ( Hiv )980 Words   |  4 Pages The Human Immunodeficiency Virus (HIV) is an immune system disorder that can be contracted through sexual activity as well as other types of contact. (Healthy Living, pg. 79) If left untreated this virus can turn into AIDS (Acquired Immunodeficiency Syndrome). AIDS is the final stage of the Human Immunodeficiency Virus (HIV). (aids.gov) AIDS is an incurable progressive disease that causes gradual destruction of CD4 T cells by the human immunodeficiency virus (HIV). (Diseases, pg. 431) A healthyRead MoreHiv, Or Human Immunodeficiency Virus998 Words   |  4 PagesQuestion 1 HIV, or Human Immunodeficiency Virus, attacks the human immune system and greatly weakens the body’s ability to fight foreign invaders and infection. HIV first demanded notice in the early 1980s in the United States in homosexual men displaying illnesses like Pneumocystis carinii pneumonia and Kaposi’s sarcoma. The disease was soon observed in IV drug users, hemophiliacs, and blood transfusion recipients, but became publicized as a â€Å"gay disease,† nicknamed by the media as GRID, or Gay-RelatedRead MoreHuman Immunodeficiency Virus ( Hiv )1349 Words   |  6 Pages Human Immunodeficiency Virus (HIV) is a retro virus that causes AIDs by infecting the T Helper cells of the body’s immune system. The AIDS virus is the final stages of the HIV virus. HIV is a lentivirus genus, which is a subgroup of the retrovirus that causes the AIDS virus. Even with proper treatment, an infected person has a life expectancy of less than ten years.As the virus weakens t he human immune systems, this effectleaves the patient compromised and at risk to opportunistic infections

Air Pollution Essay - 1780 Words

Air Pollution Earth is the only place in the universe that can support human life. It is very important that we realize this fact and take very good care of it. Various human activities cause the destruction of earth. Human beings can live a few days without food and water however humans can last only a few seconds without oxygen. Various human activities lead to the aggravation of the quality of air. Gases produced by human activities mainly due to exploitation of resources and industrialization cause air pollution. Green house gases mainly chlorofluorocarbons; carbon†¦show more content†¦Currently carbon dioxide is responsible for 57% of the global warming trend. Chlorofluorocarbons (CFC’s): CFC’s are lowering the average concentration of ozone in the stratosphere. â€Å"Since 1978 the use of CFC’s in aerosol cans has been banned in the United States, Canada and most Scandinavian countries. Aerosols are still used around the world and accounts for 25% of global CFC’s use†. (Miller 448). Spray cans discarded or leaking refrigerator and air conditioning equipment and the burning plastic foam products release the CFC’s into the atmosphere. Depending on the type, CFC’s stay in the atmosphere from 22 to 111 years.† Chlorofluorocarbons move up to the stratosphere gradually over several decades. Under high energy ultra violet (UV) radiation break them down and release chlorine atoms, which speed up the breakdown of ozone (O3) into oxygen (O2). Chlorofluorocarbons, also known as Freons, are green house gas that contributes to global warming. Photochemical air pollution is commonly referred to as â€Å"smog†. Smog is the contraction of the words smoke and fog, smog has been caused by water condensing on smoke particles, usually from burning coal. With the introduction of petroleum to replace coal economies in countries, photochemical smog has become predominant in many cities, which are located in sunny warm and dry climates with many motor vehicles. The worst episodes ofShow MoreRelatedAir Pollution essay910 Words   |  4 PagesAir pollution has become a major problem in the United States. The agricultural industry must help maintain air quality. By doing that the United States has started trying to make machines that will help reduce the pollution in the air which will help the environment. One way the United States has tried stopping air pollution and that is to create a solar powered machine which decreases air pollution. But also there are some ways that the people of the United States can help stop air pollution. Read MoreEssay On Air Pollution1500 Words    |  6 PagesIntroduction: Pollution is when a harmful or poisonous gas is emitted in the presence of air that can be very harmful to the environment even for humans, especially when we don’t do anything . We might think that pollution is not really a problem in the world but it is one major problem and some countries are suffering from it now. There are many ways that we can stop pollution about but we just don’t really take matter of it, if people will just observe how pollution is affecting the environmentRead MoreAir Pollution Essay1359 Words   |  6 Pagespremature deaths caused each year due to air pollution in cities across the world† (Air Pollution). Every day the average person inhales about 20,000 liters of contaminated air, Such as carbon dioxide and smog (Brimblecombe). These pollutants are released throughout the world’s atmosphere in concentrations that are high enough to cause health problems, which leads to one of the main problems today, and that would be air pollu tion (Socha). The main cause of air pollution is all of the toxic chemicals thatRead MoreAir Pollution Essay1322 Words   |  6 PagesAll living things use air and it must be clean to maintain life on earth. When air pollution becomes the subject, what do you think about? Smog, acid rain, and other forms of outdoor pollution are the common things people think about. Air pollution can also exist indoors as in closed ventilated areas that we surround. This makes the air that we breathe indoors inescapable and the pollution exist both indoor and outdoor. For example, hair spray usage indoor is polluting the air inside because of theRead MoreAir Pollution Essay1203 Words   |  5 PagesAir pollution can be described as any contaminate of the atmosphere that disturbs the natural composition and chemistry of the air. This can be in the form of particulate matter such as dust, or excessive gases like carbon dioxide or other vapors. These pollutants can occur naturally, or are the product of human activities. The air that we breathe is filled with substances that are hazardous to our health. Some contaminates can be noticed because of an odor, where some cannot because they are odorlessRead MoreEssay On Air Pollution1777 Words   |  8 PagesChapter 1 Introduction 1.1 Introduction Environment pollution is a wide reaching problem and it is likely to influence the health of human population is a great the systematic pollution of our environment is one of the biggest hazards that humanity faces today. Air is on of important element of earth which is compulsory for life. Air pollution may be described as contamination of the atmosphere by gaseous, liquid or solid wastes or by-products that can endanger human health and welfare of plantsRead More Air Pollution Essay2769 Words   |  12 PagesAir Pollution Among the different Civil rights and liberties Americans should be able to enjoy are the ones to breathe clean, good quality air, indoor (schools, homes, hospitals, offices, homes, sports complex, camps and churches) and outdoor, and live in areas safe from contaminated landfills, all very debated environmental policy issues. The United States Government at the federal as well as at the state and city levels is very much aware of the importance of the air pollution problem, in allRead MoreAir Pollution in China Essay747 Words   |  3 PagesAir Pollution in China When people think about air pollution, the things that come to their mind are smog, acid rain, and other forms of outdoor air pollution. Air Pollution is not a new topic. It is a problem that we have noticed since the industrial revolution, when trees, houses and cars were covered in soot from the factories. Every year, chemical substances present in the air within buildings affect the healths of thousands of people. The definition of air pollution is The presence in theRead MoreEssay Investigating Air Pollution1158 Words   |  5 PagesInvestigating Air Pollution There are many different types of air pollutant. These pollutants have different effects on the environment and on our health. Some, directly because they are harmful chemicals and others because they can react together to produce harmful chemicals. Other pollutants or pollutant combinations upset the natural balance of acidity and nitrogen in the environment which can affect the diversity of species in sensitive areas. Other pollutants canRead MoreAir Pollution - Essay 71320 Words   |  6 Pagesthink about air pollution, they usually think about smog, acid rain, CFC s, and other forms of outdoor air pollution. The health of many people is affected by chemical substances present in the air within buildings. We chose this topic to be more aware about air pollution these days because it is more harmful to our health. To know some idea on how to handle air pollution and the importance of protecting the environment. An expression implying that we live because we breathe. Fresh air is the phase

The Role of Situation Analysis for a Marketing Plan

Situation analysis becomes increasing important for a marketing plan development. This essay aims to explain why it is so important and what factors it focus on and finally, a guild list is present and justify for the construction of an effective situation analysis for a Marketing Plan of J Boag Son Brewery. Analyzing situation prior a strategic decision is critical for generating or sustaining competitive advantages, especially when facing the dynamic environmental trend which can affect corporations’ performance positively or negatively. The main task for a situation analysis is to explore the external factors (that can imply what opportunities a firm should seize and what threats it has to pay caution to) and internal factors (that†¦show more content†¦The 35mm camera market was dominated by Japanese manufacturers. Market Nature: Large, complex, fast-developing market for 35mm-camera manufacture During the 1960s and 1970s, the 35mm single lens reflex became increasingly popular. By 1980s, the trend turned to automatic rangefinder type that called ‘point and shoot’ and the disposable plastic was welcome to be used in cameras. Situation Analysis – External Factors ï‚Ÿ Legislation dimension: international tariffs are removed by GATT agreement ï‚Ÿ Social dimension: people in Europe have income and leisure time increased as well as the environmental concerns arisen in terms of chemical waste and disposal ï‚Ÿ Economic dimension: currency fluctuations of Yen would impact the price of Japanese products including camera, while manufacturing costs in German factory 15% higher than in UK ï‚Ÿ Technological dimension: automatic ‘point and shoot’ technology and cheap plastic disposable models were still popular in 1980s ï‚Ÿ New entrants: Chinese and Korean manufactures that can provide low price ï‚Ÿ Supplier power: Lens manufacturers tend to forward integrate into cameras and films making ï‚Ÿ Threat of substitutes: Digital camera is replacing traditional camera ï‚Ÿ Buyer power: not dominated by certain distributors Situation Analysis – Direct Competitor Japanese manufacturers such as Nikon and Canon which have goodShow MoreRelatedSituation Analysis in Marketing Plan Essay1585 Words   |  7 Pagesyou can fight a hundred battles with no danger of defeat’. Hence, the company must make marketing plan systematically, in terms of its objectives and missions, if it pursues maintaining a high level of operating efficiency, and achieving above-average returns. The role of situation analysis Situation analysis is an essential first step in the process of marketing plan. Jain (2004) states situation analysis is an important way in terms of forecasting the shape of things, analyzing strategic alternativesRead MoreMarketing Plan -- Situation Analysis1632 Words   |  7 PagesThe role of situation analysis in marketing plan Facing to more complex business environment, systematically marketing plans are important to organizations in terms of maintaining a high level of operating efficiency and achieving goals fully. According to Sally and John (1996:3), marketing plans are â€Å"the written document or blueprint for implementing and controlling an organization’s marketing activities related to a particular marketing strategy† (Sally, D., Lyndon S., John, B., 1996: 3). ARead MoreCompany and Marketing Strategy: Partnering to Build Customer Relationships1465 Words   |  6 Pagesmarketing’s role in strategic planning and how marketing works with its partners to create and deliver customer value 4. Describe the elements of a customer-driven marketing strategy and mix, and the forces that influence it 5. List the marketing management functions, including the elements of a marketing plan, and discuss the importance of measuring return on marketing investment Chapter Outline 1. Companywide Strategic Planning: Defining Marketing’s Role 2. Marketing Strategy and the Marketing Mix Read MoreMarketing Plan827 Words   |  4 Pagesï » ¿Marketing Business Environment Marketing Planning: An Overview of Marketing 6 main questions to ask in order to create your marketing plan: 1. Where are we now? (Business Mission, Marketing audit, SWOT analysis) 2. How did we get here? (Business Mission, Marketing audit, SWOT analysis) 3. Where are we heading? (Marketing audit, SWOT Analysis) 4. Where would we like to be? (Marketing objectives) 5. How do we get there? (Core Strategy, Marketing mix decisions, Organization, ImplementationRead MoreStrategic Marketing : Business World, Tourism And Hospitality Industry Essay1379 Words   |  6 Pagesconducted to deal with the present condition of Great Yarmouth as a tourist destination through the analysis with strategic marketing, planning process, environmental analysis and recommended some strategic options for Great Yarmouth for achieving a sustainable source of competitive advantage. Task 1: The key fundamentals of strategic marketing Strategic marketing: The ultimate goal of strategic marketing is achieving a distinctive position (i.e. above average performance) that can give it a sustainableRead MoreMarketing Plan For Tourism Macedon Ranges1482 Words   |  6 PagesExecutive summary This marketing plan is designed for Tourism Macedon Ranges in 2016; the marketing plan aims to build the awareness of the Macedon Ranges at the tourism domestic and international markets, in order to attract more visitations to the region. In same time, the marketing plan also aims to enhance the quality and variety of products and services provided by the Macedon Ranges to maximise customers’ satisfaction and travelling experience.. Other incredible sources of information wereRead MoreLiko1169 Words   |  5 PagesThe Role of Marketing Blooms: Apply AACSB: Reflective Thinking Page: 07 Value is the customers perception of all of the benefits of a product or service weighed against all the costs of acquiring and consuming it. Benefits can be functional (the performance of the product), experiential (what it feels like to use the product), and/or psychological (feelings such as self-esteem or status that result from owning a particular brand). | | 2 INCORRECT | | How did integrated marketing communicationsRead MoreMarketing Pl An Organization1658 Words   |  7 PagesWeek 8 Marketing Plan Lacey Davis A marketing plan is a strategic document outlining an organization’s advertising and marketing efforts describing its goals and objectives within a certain time period. **The components and dimensions are important in developing a marketing plan and useful to non-profit and profit organizations. A Marketing Plan assists in obtaining external funding, useful in identifying strategic alliances, and assist in gaining customer commitment, strategic plans oftenRead MoreThe Key Financial Commitments That The Company Must Make A Strategy For Managing Human Resources818 Words   |  4 Pagesinternal workers to the company to guide those responsible for achieving the financial objectives of the company. Moreover, the control tools will allow to account for the situation of the company at a given time. These are boards set up by the financial team the company that will give to the company a reflection of its situation in comparison to the sector. Moreover, the performance of Wal-Mart is directly related to the performance of women and men who compose it. A priority of the company is thereforeRead MoreCurrent Marketing Performance1166 Words   |  5 PagesBSBMKG608A: Develop organisational marketing objectives Description This unit describes the performance outcomes, skills and knowledge required to conduct a strategic analysis to develop organisational marketing objectives. This involves reviewing the organisation s internal and external environments, evaluating past and current marketing performance, and exploring and evaluating new marketing opportunities. No licensing, legislative, regulatory or certification requirements apply to this unit at

National Parks System free essay sample

Overview of system, role of Forest Service, history, legal preservation, tourism, pollution, overuse and economics. Includes examples. The National Parks Service administers the 367 parks, historical sites, and recreation areas under its purview, while the U.S. Forest Service oversees U.S. forest policy for a much broader wilderness area. When these lands were first designated a national forests, it was clear that they had been set aside for consumptive uses, but new priorities and new forces have brought into question many of the traditional guidelines for the use of this land. The political and social environment of the management of the national parks has changed many times over the years as a re-examination and a re-ordering of priorities have occurred, and as part of this process considerable conflict has been generated among different groups and factions with different ideas about what the priorities should be. Both the National Parks Service (NPS) and the Forest Service face considerable. We will write a custom essay sample on National Parks System or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page .

Impact of Plastic Debris -Free-Samples -Myassignmenthelp.com

Question: Discuss about the the Impact of Plastic Debris on the Marine Ecosystem. Answer: Introduction: The aim of the assignment is to study the impact of plastic debris on the marine ecosystem. The study is based on three literary sources. The first source is the video titled Plastic Paradise by media journalist Angela Sun, which speaks about the Midway Inlands in the Pacific Ocean and the devastating level of plastic debris, which collect on and around its shores. The second literary case is an article published in the English newspaper the Daily Mail by Liberatore which speaks about the immense quantities of plastics which reach the ocean along the biggest rivers in the world (dailymail.co.uk, 2017). The book by Charles W. Hill mentions current events like globalisation and international trade. An analysis of these three cases shows that though they look unrelated, they are heavily related to each other. It is this relatedness between these three literary sources, which make it important to combine them to realise the full meaning and benefit from them. Sun in her article speaks ab out the devastating impact plastic debris has on the marine ecosystem. She states that birds, fishes and other marine mammals due to suffocation and poisoning by the plastic. These have devastating impact on the industries like fishing and restaurant, which obtain raw materials from these marine animals. The plastic break down into minute pieces, which are embedded into the bodies of the marine animals, and finally the human beings who eat these animals. Moreover, the nets of nylon destroy coral reefs, which form sources of food for the ecosystem and medicines for fatal diseases like cancer (Holm, Eriksson Johanson, 2015). The minute pieces of plastic enter human bodies and causes hormonal imbalances, brain damage and finally death. It is thus huge scale of pollution by plastic and its devastating impacts on all living things including man make the matter through the literary sources important to study (Arora et al., 2017). Thus, the impact of this large-scale pollution due to plas tic and plastic nets is poisoning of the coral reefs. Fishes that in turn get the minute plastic pieces in their bodies consume the poisonous corals. These minute pieces enter the human bodies when they these fishes. The plastic damages the physiological systems in the body leading towards death. Thus, the impact of the plastic pollution in the oceans is nemesis for all the living creatures on earth including man (Padhy Mishra, 2015). An analysis of the video by Sun and the article by Liberatore shows that a major portion of debris is composed of bottles, air condition parts, boxes and other packages. It can be pointed out that this immense amount of packages belongs to goods produced by the FMCG companies all round the world. The consumers of the fast moving consumer goods (FMCG) consume the products and dump their plastic packages into rivers. These excessive applications of plastic in the FMCG goods have made the FMCG industry to the target industry for the study on impact of plastic on the oceans (Zheng, 2013). Current events: The current events mentioned of the three literary sources consists of a video available Youtube called Plastic Paradise, a newspaper article from the international English language daily, the Daily Mail on river pollution caused due to plastic and a book. The name of the book is International Business by Charles W. Hill, University of Washington. The sections that follow would analyse and discuss the similarities and differences between the book, the video and the newspaper article. Differences and similarities between the three literary sources: There are several similarities and differences between the three literary sources the author has chosen namely, the video, the newspaper article and the book. The following two sections would analyse these differences and similarities: Differences between the three literary sources: The first difference between the Youtube video, the Daily Mail article and the book is their area of coverage. The video titled Plastic Paradise deals with dumping plastic in the oceans and how the ocean currents go in circular forms washing these plastic dump up to the shores of surrounding landmasses both large continents and small islands. The video concentrates more on the Pacific Ocean and the Midway Islands in it, which has earned the name Plastic Island owing to tonnes of plastic debris, which the currents wash up the islands shores (youtube.com, 2017). The article in the Daily Mail speaks about the herculean scale of river pollution in the main rivers across the world due to plastic dumps. The article, unlike the video concentrates mainly on the ten main rivers on earth like Yang Tze and the Ganges, which add ninety percent of the oceans plastic content. The book does not speak about pollution due to plastic in water bodies, instead speaks about globalisation, economic develo pment and religions (Hill, 2017). The second point of difference between the three literary sources lie in their treatment of the topics they explain. The video speaks about the dangerous effect plastic is having on the environment, oceans and the living things. The video spans across diverse topics like plastic production, use of plastic, its impact on the marine creature, how it enters the food chains and finally how it devastates the bodies of living organisms. The video clearly shows how presence of plastics in the fishes and marine creatures harm the industries like restaurant industries around the world to which these creatures function as raw materials. It, in other words shows how irresponsible profit making propensity of one industry namely the gas and chemical industries making plastics prove harmful for other industries namely, the restaurant and the fishing industry in the long run. The book treats diverse range of topics namely globalisation, international trade and marketing. The book does not speak abo ut pollution but globalisation, which is one of the leading causes of pollution (Hill, Jones Schilling, 2014). Similarities between the literary sources: The first similarity between the three literary sources is that they speak about pollution. The video shows that multitude of marine pollution in oceans namely the Pacific Ocean due to plastic debris from the economic giants Asia and North America. The video also attribute the inflow of plastic articles like bottles, cans and packages mostly from the fast moving consumer goods to the ships and boats voyaging the oceans (Jambeck et al., 2015). The newspaper articles too point out to the multitude of pollution due to plastic in the rivers and ultimately to the seas and oceans. Thus, it can be analysed that the newspaper indirectly speaks about the enormous amount of plastic items, which find ways into the oceans. The article in fact, concludes with the mention of the Midway Islands in the Pacific Ocean, the main feature the video. This shows that the article from the Daily Mail and the video actually point at the same point which is, impact of plastic debris on marine environment and consequently to all living things on earth including man (trach Wiesinger, 2015). The book speaks about topics like globalisation and market entry strategies. One can point out that globalisation has led to rapid industrialisation which in turn leads to generate unimaginable amount of sewage. It can be pointed that industries like FMCG have entered virtually every economy and cater to the global consumer base. These industries use enormous amount of plastic for packing and packaging their products. Thus, globalisation and expansion of industries like FMCG has led to outflow of enormous amount of plastic into the rivers and finally the oceans. Thus, the book indirectly speaks about pollution of water bodies like rivers and oceans (Srinivasan Lu, 2014). The second similarity between the video, article and the book is that they speak about management of resources in sustainable ways. The video shows that irresponsible actions of the plastic companies producing plastic goods, FMCG companies who use it to package and pack their products and the consumers who use both the items devastate the biomes on the earth, slowly and gradually. It states that the minute pieces of plastic gradually enter the food chains when fishes and marine creatures eat them which either causes their death or makes them unfit for human consumption. This deteriorating quality of the fishes is raking havoc on the industries like restaurant, marine food, fishing and tourism. Thus, in other words, industries are able to affect each other through their actions (Padhy Mishra, 2015). The newspaper speaks about how these industries dump plastic, which flows out into the oceans. An analysis of the article clearly point out how lack of sustainable sewage disposable metho ds in the factories situated on the rivers ultimately lead to ocean pollution. For example, the plastic sewage of the Ganges ultimately pollutes the Indian Ocean and the plastic discharge of the Yang Tze pollutes the Pacific waters. The book also speaks about human resources, globalisation and international trade, all of which promote responsible operation of companies in crucial areas like sustainability (Eriksen et al., 2013). Political orientation behind the perspective of the materials originator: There are no clear political intentions, which made the authors of the video, newspaper article or the book, which motivated them to form these three literary sources. It is maker of the video have similar inclination. Their inclination was to create awareness about the devastating effect plastic has on the marine life and consequently on the entire ecosystem. The inclination of Charles W. L. Hill to write the book is to educate the readers, chiefly the university students on globalisation and related topics like international trade. The author of the newspaper article by Stacy Liberatore does not bear any political inclination since the author apparently has no political background. The main narrator of the video Plastic Paradise-the Great Pacific Garbage Patch, Angela Sun, is a media journalist. The video apparently does not show any intention to politicise pollution. Thus, it can be summarised from the discussion that the authors of the literary sources namely, the British daily, the video and the book have no political orientation (Vegter et al., 2014). The authors of the newspaper article, video and the book are Stacy Liberatore, Angela Sun and Hill respectively. They apparently have no political orientation behind writing or making these videos and articles. First, the author of the newspaper article, Liberatore is apparently a homemaker who works as a freelancer and lives in America. She in the article in the English daily expresses serious concern about the devastating impact plastic debris is having on the rivers. She pointed out that the rivers in the world like the Ganges of India and the Yang Tze of China with largest discharge of water carry with them millions of tonnes of plastic debris into the ocean they flow. She concluded the article by mentioning the Midway Islands, which has earned the name Plastic Island wing to the immense amount of plastic debris the Pacific Ocean has washed up its shores (Sirirat, 2017). The main narrator of the video Angella Sun is a media journalist who apparently does not showcase any kind of political orientation. She introduces several environmentalists like Charles Moore and Dr Susan Freinkal in her video, which shows her intention of gaining strong participation of the environmentalists. The video clearly shows her strong intention of creating awareness in the society regarding the fatal impacts of presence of plastics in the marine ecosystem and gradually into the global food chainb (Eriksen et al., 2014). Charles W. L. Hill is an academic expert and world famous professor having experiences of teaching in some of the most reputed universities in the United States. After conducting an analysis of the backgrounds of the three authors, one can arrive at the decision that they have no political intention. Development of awareness and knowledge about the video, article and book: The cases presented in the article by Liberatore, the video by Sun and the book by Hill help in development of awareness and knowledge in the society. These literary sources complement each other and strengthen each others messages. Liberatore in the article published in the English daily spoke about the dangerous level of plastic effluents the major rivers carry to the oceans (dailymail.co.uk, 2017). Sun in her video clearly shows that harm plastic debris can do to marine life. She clearly points out the danger plastic debris pose to the ecosystem of the oceans and the world as whole. Hill in the book spoke one of the most spectacular current events which has escalated the level of pollution by infinite levels, globalisation. Hill, in his book deals in concepts like globalisation and international trade. It can be pointed out that globalisation and uncontrolled international trade are the reasons for pollution (Hill, 2017). This discussion shows that the three literary articles comp lement each other. Takeaways from the assignment: An comparison and contrast between the three literary sources namely, the newspaper article, the book and the video provide three assignment take aways or lessons about the devastating impact of plastic debris. The following section would discuss the three learnings form the point of view of the FMCG industry: Plastic debris is harmful to marine life: The plastic debris float consisting of containers of FMCG products and fishing nets float in the ocean water. The marine animals are trapped in them and are either killed or injured. The macro plastics items like nylon fishing nets destroy coral reefs and disturb the food chain permanently. These big pieces of plastic break into smaller or even invisibly small plastic pieces, which become a part of the body component of the marine animals and ultimately the consumers of them including man (Unnamalai, 2017). The FMCG companies and the consumers should use and dispose plastic responsibly: The video by Sun shows that the mass of debris on the Midway Island is composed of bottles, packages and other plastic articles, which the FMCG industry uses to pack and package goods. The industry should use plastic more responsibly by recycling the plastic pieces discarded. They must create awareness among the consumers about the fatal impact of plastic accumulation in the environment. This would result in decrease in the disposal of plastic in the oceans. Plastic causes harmful impact on the human body: The book by Hill states that globalisation and foreign trade have resulted in production of goods in large scale, which has in turn multiplied pollution. Sun in her video clearly states that the enormous amount of plastic the industrial sector and the consumers use finds its way in the marine food chain. Liberatore states that the rivers also contribute to the marine pollution. The micro plastic particles enter the bodies of the fishes and the body of men to who consume those fishes. The plastic disrupts the normal working of human body by causing hormonal imbalance and diseases like cancer. Thus, plastic accumulation in the ecosystem can lethal to all living organisms including man (Padhy Mishra, 2015). Conclusion: The discussion above shows how devastating pollution can be to the living world including man. It shows that plastic debris from the industrialised nations, which reach the oceans directly or indirectly along rivers, are capable of devastating marine life. They destroy the marine eco-system, which influence the entire food chain. The microforms of plastic make fishes and marine creatures unfit for use in the restaurants and by domestic consumers. Thus the plastic pollution have gives fatal blows to the industries which depend on marine creatures for raw materials like restaurants and fish export industry. The discussion shows that companies producing and using plastic should dispose plastics more responsibly by treating and recycling them. The consumers must reuse plastic packages and not dispose them into the rivers. This would help in reduction of devastation of marine life by plastic, save the eco system, ensure continuous flow of raw materials to the restaurant industries and ens ure sustenance of life on earth. References: Agrawal, A. D., Das, M. (2013). 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